Description

3,5-Diiodo-3Ah-Indole-2-Carboxylic Acid is a high-purity, halogenated indole derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a functionalized, iodinated scaffold essential for constructing complex molecules, particularly in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its reactive iodine atoms for further functionalization.
• Agrochemical Synthesis: Serves as a precursor in the development of new active ingredients for crop protection products.
• Chemical Biology Probes: Utilized in the creation of molecular probes and labeled compounds for biochemical assays and imaging.
• Material Science: Potential intermediate for the synthesis of organic electronic materials and specialty polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and scale-up projects.

Basic Information

Product Name	3,5-Diiodo-3Ah-Indole-2-Carboxylic Acid
CAS No.	866149-84-0
Molecular Formula	C9H5I2NO2
Molecular Weight	428.95 g/mol
Synonyms	3,5-Diiodo-1H-indole-2-carboxylic acid; 1H-Indole-2-carboxylic acid, 3,5-diiodo-; 3,5-Diiodoindole-2-carboxylic Acid; 2-Carboxy-3,5-diiodoindole; Diiodoindolecarboxylic Acid; 866149-84-0; AI3-52662
EINECS	Contact for details

Quality Control

Our 3,5-Diiodo-3Ah-Indole-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Assay	95.0% - 105.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.