Description

2-Isobutylidene-2,3,4,9-Tetrahydro-Carbazol-1-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and contract development and manufacturing organizations (CDMOs) engaged in innovative drug development.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, especially those with carbazole-based pharmacophores.
• Organic Synthesis Building Block: Used in research-scale and pilot-scale organic reactions to construct novel molecular frameworks for medicinal chemistry.
• CNS Drug Development: Serves as a core structure in the research and development of potential therapeutics targeting neurological disorders.
• Oncological Research: Investigated as a starting material for compounds with potential anti-cancer activity in preclinical studies.
• Academic & Industrial R&D: Utilized in universities and corporate R&D centers for exploring new chemical entities and reaction methodologies.
• Custom Synthesis: Supplied for bespoke manufacturing projects where specific, high-purity intermediates are required for client-specific API synthesis.

Basic Information

Item	Details
Product Name	2-Isobutylidene-2,3,4,9-Tetrahydro-Carbazol-1-One
CAS No.	866149-31-7
Molecular Formula	C16H17NO
Molecular Weight	239.32 g/mol
Synonyms	2-(2-Methylpropylidene)-2,3,4,9-tetrahydro-1H-carbazol-1-one; 2-Isobutylidene-1,2,3,9-tetrahydro-4H-carbazol-4-one; 2,3,4,9-Tetrahydro-2-isobutylidene-1H-carbazol-1-one; Carbazol-1-one, 2,3,4,9-tetrahydro-2-(2-methylpropylidene)-; 866149-31-7; 2-Isobutylidene-2,3,4,9-tetrahydrocarbazol-1-one
EINECS	Contact for details

Quality Control

Our 2-Isobutylidene-2,3,4,9-Tetrahydro-Carbazol-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.