Description

Dimethyl 2-(4-[(2-Thienylcarbonyl)Amino]Phenyl)Malonate is a high-purity, specialized organic compound featuring a malonate ester core linked to a thiophene carboxamide moiety. This unique molecular architecture makes it a critical building block (advanced intermediate) in sophisticated organic synthesis, particularly for pharmaceuticals and agrochemicals. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for constructing complex target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, inflammation, or metabolic diseases.
• Agrochemical Synthesis: Used as a building block for developing new generation herbicides, fungicides, or insecticides with enhanced efficacy and selectivity.
• Material Science Research: Serves as a monomer or functional component in the development of advanced organic electronic materials, such as semiconductors or sensitizers for dye-sensitized solar cells (DSSCs).
• Ligand and Catalyst Development: The thiophene and amide functionalities make it a candidate for constructing complex ligands used in asymmetric catalysis or metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	Dimethyl 2-(4-[(2-Thienylcarbonyl)Amino]Phenyl)Malonate
CAS No.	866137-15-7
Molecular Formula	C16H15NO5S
Molecular Weight	333.36 g/mol
Synonyms	Dimethyl (4-{[(thiophen-2-yl)carbonyl]amino}phenyl)propanedioate; 2-(4-[(2-Thienylcarbonyl)amino]phenyl)malonic acid dimethyl ester; Propanedioic acid, 2-[4-[(2-thienylcarbonyl)amino]phenyl]-, 1,3-dimethyl ester; (4-{[(Thiophene-2-carbonyl)-amino]-phenyl})-malonic acid dimethyl ester
EINECS	Contact for details

Quality Control

Our Dimethyl 2-(4-[(2-Thienylcarbonyl)Amino]Phenyl)Malonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.