Description

Ethyl 5-Benzyloxy-1H-Indazole-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the indazole class of heterocyclic compounds. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and neurological research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting specific enzymatic pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• API Development: Integral in the research and process development stages for new Active Pharmaceutical Ingredients (APIs).
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and scale-up services for the pharmaceutical industry.
• Biochemical Reagent: May be utilized in biochemical assays as a reference standard or inhibitor compound in laboratory settings.

Basic Information

Product Name	Ethyl 5-Benzyloxy-1H-Indazole-3-Carboxylate
CAS No.	865887-17-8
Molecular Formula	C17H16N2O3
Molecular Weight	296.32 g/mol
Synonyms	Ethyl 5-(Benzyloxy)-1H-indazole-3-carboxylate; 5-Benzyloxy-1H-indazole-3-carboxylic acid ethyl ester; 1H-Indazole-3-carboxylic acid, 5-(phenylmethoxy)-, ethyl ester; Ethyl 5-(phenylmethoxy)-1H-indazole-3-carboxylate; 865887-17-8; 5-Benzyloxyindazole-3-carboxylic Acid Ethyl Ester; 5-O-Benzyl-1H-indazole-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-Benzyloxy-1H-Indazole-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.