Description

2-([2-(4-Fluorophenyl)-1H-Indol-3-Yl]Thio)Ethanamine is a high-purity, advanced pharmaceutical intermediate characterized by its unique indole-thioether-amine structure. This compound is critical for the research and development of novel therapeutic agents, particularly in the fields of oncology and central nervous system (CNS) disorders. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of investigational new drugs (INDs) and new chemical entities (NCEs), particularly those targeting kinase inhibition.
• Oncology Research: Serves as a core scaffold for developing potential anti-cancer compounds due to the indole moiety's prevalence in many chemotherapeutic agents.
• CNS Drug Discovery: Used in medicinal chemistry programs aimed at creating novel treatments for neurological and psychiatric conditions.
• Biochemical Research: Employed as a reference standard or a probe molecule in biochemical assays and target validation studies.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) specializing in the production of complex, non-commercial APIs for clinical trials.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2-([2-(4-Fluorophenyl)-1H-Indol-3-Yl]Thio)Ethanamine
CAS No.	865546-48-1
Molecular Formula	C₁₆H₁₅FN₂S
Molecular Weight	286.37 g/mol
Synonyms	2-[(2-(4-Fluorophenyl)-1H-indol-3-yl)sulfanyl]ethanamine; 2-((2-(4-Fluorophenyl)-1H-indol-3-yl)thio)ethan-1-amine; 2-([2-(4-Fluorophenyl)-1H-Indol-3-Yl]Thio)Ethan-1-Amine; 2-[(2-(4-Fluorophenyl)-1H-indol-3-yl)thio]ethylamine; 4-Fluoro-2-(2-aminoethylthio)indole; Ethanamine, 2-[[2-(4-fluorophenyl)-1H-indol-3-yl]thio]-; 865546-48-1
EINECS	Contact for details

Quality Control

Our 2-([2-(4-Fluorophenyl)-1H-Indol-3-Yl]Thio)Ethanamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.