Description

1-[(4-Fluorophenoxy)Methyl]-6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline CAS NO 865546-37-8 is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, serving as a key building block for synthesizing novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new drug candidates, particularly in the areas of central nervous system (CNS) and cardiovascular research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• CNS Drug Development: Employed in the research of potential therapeutics for neurological and psychiatric disorders due to its tetrahydroisoquinoline core.
• Cardiovascular Agent Synthesis: Serves as a building block for compounds being investigated for hypertension and other cardiovascular conditions.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological pathways and target validation.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	1-[(4-Fluorophenoxy)Methyl]-6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline
CAS No.	865546-37-8
Molecular Formula	C18H20FNO3
Molecular Weight	317.36 g/mol
Synonyms	1-[(4-Fluorophenoxy)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline; 6,7-Dimethoxy-1-[(4-fluorophenoxy)methyl]-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-6,7-dimethoxy-1-[(4-fluorophenoxy)methyl]isoquinoline; 1-(4-Fluorophenoxymethyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline; 865546-37-8; Tetrahydroisoquinoline derivative, fluorophenoxy substituted
EINECS	Contact for details

Quality Control

Our 1-[(4-Fluorophenoxy)Methyl]-6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.