Description

1-(3-Bromopropyl)-1H-Pyrrole-2,5-Dione is a versatile brominated maleimide derivative, a key synthetic intermediate prized for its reactive bromopropyl and maleimide functional groups. This compound is essential for researchers and manufacturers requiring a reliable building block for constructing complex molecules, particularly in pharmaceutical and advanced material synthesis. It is primarily used by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty polymer industries to introduce functional handles for conjugation, cross-linking, and further chemical elaboration.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for creating maleimide-linked bioconjugates and targeted drug delivery systems.
• Bioconjugation Reagent: Used to functionalize proteins, antibodies, or peptides via thiol-maleimide chemistry, enabling the attachment of drugs, dyes, or other payloads in biopharmaceutical development.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polymers, including functionalized resins, hydrogels, and materials with tailored surface properties.
• Agrochemical Synthesis: Employed as an intermediate in the research and production of novel crop protection agents and herbicides.
• Chemical Research: A valuable reagent in organic synthesis for constructing heterocyclic compounds and exploring new reaction methodologies in academic and industrial laboratories.
• Material Science: Used to modify surfaces or create advanced functional materials with specific chemical reactivity or biological compatibility.

Basic Information

Product Name	1-(3-Bromopropyl)-1H-Pyrrole-2,5-Dione
CAS No.	864937-28-0
Molecular Formula	C7H8BrNO2
Molecular Weight	218.05 g/mol
Synonyms	N-(3-Bromopropyl)maleimide; 3-Bromopropylmaleimide; 1-(3-Bromopropyl)maleimide; Maleimide, N-(3-bromopropyl)-; 1H-Pyrrole-2,5-dione, 1-(3-bromopropyl)-; N-(3-Bromopropyl)-2,5-dihydro-1H-pyrrole-2,5-dione; 3-Bromopropyl maleimide; N-(3-Bromopropyl)maleimide
EINECS	Contact for details

Quality Control

Our 1-(3-Bromopropyl)-1H-Pyrrole-2,5-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber glass, or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.