Description

tert-Butyl 5-Bromo-1-oxoisoindoline-2-carboxylate is a high-purity, protected isoindolinone derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive bromine handle and a tert-butyloxycarbonyl (Boc) protecting group, enabling precise molecular construction for complex targets. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex heterocyclic compounds and potential drug candidates, especially those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its brominated isoindolinone scaffold.
• Material Science: Building block for creating specialized polymers and organic electronic materials with tailored properties.
• Academic & R&D: Serves as a versatile starting material in medicinal chemistry and organic synthesis research for method development and library synthesis.
• Peptidomimetics: The Boc-protected lactam structure is useful in the design and synthesis of peptidomimetic compounds.

Basic Information

Product Name	tert-Butyl 5-Bromo-1-oxoisoindoline-2-carboxylate
CAS No.	864866-80-8
Molecular Formula	C13H14BrNO3
Molecular Weight	312.16 g/mol
Synonyms	5-Bromo-2-[(tert-butoxy)carbonyl]isoindolin-1-one; 2-Boc-5-bromoisoindolin-1-one; 1(2H)-Isoindolinone, 5-bromo-2-[(1,1-dimethylethoxy)carbonyl]-; 5-Bromo-2-(tert-butoxycarbonyl)isoindolin-1-one; tert-Butyl 5-bromo-1-oxo-2,3-dihydro-1H-isoindole-2-carboxylate; 5-Bromo-2-(Boc)isoindolin-1-one; Boc-5-Bromo-isoindolinone
EINECS	Contact for details

Quality Control

Our tert-Butyl 5-Bromo-1-oxoisoindoline-2-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.