Description

(4-Chlorophenyl)(8-Methoxy-1,3,4,5-Tetrahydro-2H-Pyrido[4,3-B]Indol-2-Yl)Methanone is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the research and development of new drug candidates, particularly those targeting neurological pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the multi-step synthesis of complex APIs, especially those containing tetrahydro-β-carboline and related indole alkaloid frameworks.
• Biochemical Research: Utilized as a tool compound in biochemical assays to study receptor binding and enzyme inhibition.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects under cGMP conditions.

Basic Information

Product Name	(4-Chlorophenyl)(8-Methoxy-1,3,4,5-Tetrahydro-2H-Pyrido[4,3-B]Indol-2-Yl)Methanone
CAS No.	864762-58-3
Molecular Formula	C20H19ClN2O2
Molecular Weight	354.83 g/mol
Synonyms	8-Methoxy-2-[(4-chlorophenyl)carbonyl]-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indole; (4-Chlorophenyl)(8-methoxy-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)methanone; 2-(4-Chlorobenzoyl)-8-methoxy-1,2,3,4,5,6-hexahydropyrido[4,3-b]indole; Tetrahydro-β-carboline derivative; 864762-58-3; 8-Methoxy-THBC amide
EINECS	Contact for details

Quality Control

Our (4-Chlorophenyl)(8-Methoxy-1,3,4,5-Tetrahydro-2H-Pyrido[4,3-B]Indol-2-Yl)Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment. We support development under ICH guidelines and can discuss custom specifications for cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.