Description

Fluralaner is a potent isoxazoline-class insecticide and acaricide that acts as a highly selective antagonist of invertebrate GABA-gated chloride channels. This mode of action provides rapid and long-lasting efficacy against a broad spectrum of ectoparasites. It is a critical active ingredient for the animal health and veterinary pharmaceutical industries, primarily used in formulations for companion animals and livestock. Global demand is driven by the need for effective, long-acting parasite control solutions.

Application

• Veterinary Pharmaceuticals: Primary active ingredient in topical "spot-on" solutions and oral chews for dogs and cats to control fleas and ticks.
• Livestock Parasite Control: Used in formulations for poultry (e.g., against poultry red mites) and potentially other livestock for systemic parasite management.
• Animal Health Intermediates: Serves as a key raw material (API) for manufacturers developing end-use veterinary medicinal products.
• Research & Development: Utilized in biochemical and pharmacological studies targeting invertebrate nervous systems and for developing new parasiticides.
• Public Health Vector Control: Investigated for potential use in controlling ectoparasites that transmit diseases, subject to regional regulatory approvals.

Basic Information

Product Name	Fluralaner
CAS No.	864731-61-3
Molecular Formula	C22H17Cl2F6N2O3
Molecular Weight	556.28 g/mol
Synonyms	Fluralaner; 4-[5-(3,5-Dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]-2-methyl-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]benzamide; A1443; BAY 2744; Bravecto (Trade Name for formulated product); Isoxazoline insecticide; GABA-gated chloride channel antagonist
EINECS	Contact for details

Quality Control

Our Fluralaner is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency, suitable for pharmaceutical applications. Quality is verified through comprehensive analytical testing including HPLC, GC, and NMR. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and formulation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.