Description

7-Fluoro-4-Methoxy-Benzo[B]-Thiophene-2-Carboxylic Acid, Methyl Ester is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a critical intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific fluorinated and methoxy-substituted benzothiophene motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Development: Used in creating advanced active ingredients for crop protection products, where the fluorine atom can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for organic electronic materials, such as semiconductors or light-emitting components, due to its conjugated benzothiophene core.
• Chemical Biology Probes: Employed in the design and synthesis of fluorinated probes and ligands for studying enzyme mechanisms and receptor binding.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	7-Fluoro-4-Methoxy-Benzo[B]-Thiophene-2-Carboxylic Acid, Methyl Ester
CAS No.	864685-38-1
Molecular Formula	C11H9FO3S
Molecular Weight	240.25 g/mol
Synonyms	Methyl 7-Fluoro-4-methoxybenzo[b]thiophene-2-carboxylate; 7-Fluoro-4-methoxy-1-benzothiophene-2-carboxylic acid methyl ester; 2-Methoxycarbonyl-7-fluoro-4-methoxybenzo[b]thiophene; 864685-38-1; Benzo[b]thiophene-2-carboxylic acid, 7-fluoro-4-methoxy-, methyl ester
EINECS	Contact for details

Quality Control

Our 7-Fluoro-4-Methoxy-Benzo[B]-Thiophene-2-Carboxylic Acid, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong alkalis and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.