Description

6-Ethyl-3-Hydroxy-3-(2-Oxo-2-Pyridin-2-Yl-Ethyl)-1,3-Dihydro-Indol-2-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant commercial interest for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of new chemical entities (NCEs) for drug discovery programs.
• API Synthesis: Serves as a critical precursor in the multi-step synthesis of potential active pharmaceutical ingredients, especially those targeting neurological or oncological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	6-Ethyl-3-Hydroxy-3-(2-Oxo-2-Pyridin-2-Yl-Ethyl)-1,3-Dihydro-Indol-2-One
CAS No.	864685-13-2
Molecular Formula	C₁₇H₁₆N₂O₃
Molecular Weight	296.32 g/mol
Synonyms	6-Ethyl-3-hydroxy-3-[2-oxo-2-(pyridin-2-yl)ethyl]indolin-2-one; 2H-Indol-2-one, 1,3-dihydro-6-ethyl-3-hydroxy-3-[2-oxo-2-(2-pyridinyl)ethyl]-; 3-Hydroxy-6-ethyl-3-[2-oxo-2-(pyridin-2-yl)ethyl]indolin-2-one; 6-Ethyl-3-hydroxy-3-(2-oxo-2-(pyridin-2-yl)ethyl)indolin-2-one; CAS 864685-13-2
EINECS	Contact for details

Quality Control

Our 6-Ethyl-3-Hydroxy-3-(2-Oxo-2-Pyridin-2-Yl-Ethyl)-1,3-Dihydro-Indol-2-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing batch-specific results are available upon request, supporting your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.