Description

1-(5-Bromo-2-Methoxy-Benzyl)-Pyrrolidine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct brominated methoxybenzyl-pyrrolidine structure. This compound is critical for enabling precise molecular modifications in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up API synthesis routes from lab to pilot plant.
• Biochemical Tool Compound: May be utilized in the development of receptor ligands or enzyme inhibitors for pharmacological research.
• Custom Synthesis: Employed by fine chemical manufacturers for producing bespoke compounds under contract research and manufacturing (CRAM) agreements.

Basic Information

Product Name	1-(5-Bromo-2-Methoxy-Benzyl)-Pyrrolidine
CAS No.	864418-18-8
Molecular Formula	C₁₂H₁₆BrNO
Molecular Weight	270.17 g/mol
Synonyms	1-[(5-Bromo-2-methoxyphenyl)methyl]pyrrolidine; 5-Bromo-2-methoxybenzylpyrrolidine; Pyrrolidine, 1-[(5-bromo-2-methoxyphenyl)methyl]-; 864418-18-8; 1-(5-Bromo-2-methoxybenzyl)pyrrolidine; (5-Bromo-2-methoxybenzyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our 1-(5-Bromo-2-Methoxy-Benzyl)-Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.