Description

(2-[(tert-Butoxycarbonyl)Amino]Pyridin-3-Yl)Boronic Acid CAS NO 863753-35-9 is a high-value, protected aminopyridine boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in its dual functionality, where the boronic acid group enables Suzuki-Miyaura cross-coupling reactions, and the Boc-protected amine provides orthogonal reactivity for further derivatization. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, specifically for constructing complex heterocyclic scaffolds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Suzuki-Miyaura Cross-Coupling: Used as a boronic acid coupling partner to introduce the 3-aminopyridine moiety into complex molecules under mild conditions.
• Agrochemical Synthesis: Building block for creating advanced herbicides and fungicides with specific targeting properties.
• Material Science Research: Precursor for functionalized ligands and monomers used in organic electronic materials.
• Chemical Biology Probes: Utilized in the development of tagged molecules for studying biological pathways and protein interactions.
• Peptidomimetics: Incorporation into peptide analogs to enhance stability and bioavailability.

Basic Information

Product Name	(2-[(tert-Butoxycarbonyl)Amino]Pyridin-3-Yl)Boronic Acid
CAS No.	863753-35-9
Molecular Formula	C₁₀H₁₅BN₂O₄
Molecular Weight	238.05 g/mol
Synonyms	3-(Boc-amino)-2-pyridineboronic acid; 2-((tert-Butoxycarbonyl)amino)-3-pyridineboronic acid; 2-(Boc-amino)pyridin-3-ylboronic acid; N-Boc-3-aminopyridine-2-boronic acid; 2-(tert-Butoxycarbonylamino)pyridine-3-boronic acid; 3-Pyridineboronic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-; Boc-3-Amino-2-pyridylboronic acid
EINECS	Contact for details

Quality Control

Our (2-[(tert-Butoxycarbonyl)Amino]Pyridin-3-Yl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing purity, identity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and moisture-sensitive nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.