Description

(2-Aminophenyl)Boronic Acid Hydrochloride is a bifunctional organoboron compound that serves as a versatile building block in modern synthetic chemistry. Its dual functionality, combining a boronic acid group with a primary amine, makes it a critical intermediate for constructing complex molecular architectures via cross-coupling and condensation reactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science & OLED Development: Building block for synthesizing organic semiconductors, light-emitting materials, and other functional polymers used in electronic devices.
• Ligand & Catalyst Preparation: Serves as a precursor for creating specialized bidentate ligands used in asymmetric catalysis and transition metal complexes.
• Bioconjugation & Probe Synthesis: Utilized in the development of biochemical probes, sensors, and antibody-drug conjugates (ADCs) due to its reactive handles.
• Academic & R&D Laboratories: Fundamental reagent for methodological development in organic synthesis and medicinal chemistry research.

Basic Information

Product Name	(2-Aminophenyl)Boronic Acid Hydrochloride
CAS No.	863753-30-4
Molecular Formula	C6H9BClNO2
Molecular Weight	173.41 g/mol
Synonyms	2-Aminophenylboronic Acid HCl; (2-Aminophenyl)boronic Acid Hydrochloride; 2-Aminobenzeneboronic Acid Hydrochloride; o-Aminophenylboronic Acid Hydrochloride; B-(2-Aminophenyl)boronic Acid Hydrochloride; 2-Amino-Benzeneboronic Acid Hydrochloride; (2-Amino)phenylboronic Acid Hydrochloride; 2-ABPA HCl
EINECS	Contact for details

Quality Control

Our (2-Aminophenyl)Boronic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent oxidation and hydrolysis. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.