Description

n-Methylformamide-D5 is a deuterated isotopologue of N-methylformamide, where five hydrogen atoms are replaced with deuterium. This high-purity labeled compound is essential for advanced analytical and research applications where isotopic tracing and signal differentiation are required. It is primarily utilized by researchers and process developers in the pharmaceutical, agrochemical, and material science industries for applications such as NMR spectroscopy and reaction mechanism studies.

Application

• NMR Spectroscopy: Used as a deuterated solvent or internal standard for nuclear magnetic resonance studies, providing a non-interfering signal background.
• Pharmaceutical Research: Employed as a labeled reagent or intermediate in the synthesis of deuterated drug candidates for metabolic and pharmacokinetic (DMPK) studies.
• Mechanistic Studies: Serves as a tracer in chemical reaction pathways to elucidate mechanisms and kinetic isotope effects.
• Analytical Chemistry: Acts as a reference standard in mass spectrometry and other analytical techniques for quantitative analysis.
• Material Science: Utilized in the development of specialty polymers and advanced materials where deuterium incorporation modifies physical properties.
• Agrochemical Development: Applied in the synthesis of labeled pesticides or herbicides for environmental fate and metabolism studies.

Basic Information

Product Name	n-Methylformamide-D5
CAS No.	863653-47-8
Molecular Formula	C₂D₅NO
Molecular Weight	79.11 g/mol
Synonyms	N-Methylformamide-d5; Deuterated N-Methylformamide; N-Methylformamide (D5); N-Methyl-d5-formamide; Formamide, N-methyl-d5-; [2H5]-N-Methylformamide; NMF-d5; Perdeuterated N-Methylformamide
EINECS	Contact for details

Quality Control

Our n-Methylformamide-D5 is produced under controlled conditions to ensure high isotopic and chemical purity, meeting the stringent requirements of research and development. Each batch undergoes comprehensive analysis, including NMR and GC/MS, to verify deuterium incorporation and purity levels. A Certificate of Analysis (COA) detailing specific results for isotopic purity, chemical purity, and solvent residues is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect purity and stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Isotopic Purity (D-content)	≥ 98 atom % D
Chemical Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.