Description

7-Chloro-α-Oxo-1H-Indole-3-Acetyl Chloride is a high-value, reactive chemical intermediate characterized by its indole-based structure and acid chloride functionality. This compound is critical for the synthesis of complex molecules, particularly in pharmaceutical research and development, where it serves as a key building block. It is primarily sought after by fine chemical manufacturers and R&D laboratories engaged in the creation of novel active pharmaceutical ingredients (APIs) and agrochemicals. Its precise structure enables targeted modifications, making it essential for advanced medicinal chemistry projects.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel indole-based drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and fungicides with specific biological activity.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for constructing complex heterocyclic compounds and for introducing the acetyl chloride moiety.
• Bioconjugation & Probe Development: Utilized in the creation of chemical probes and affinity labels for biochemical and proteomics research due to its reactive carbonyl chloride group.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	7-Chloro-α-Oxo-1H-Indole-3-Acetyl Chloride
CAS No.	863289-28-5
Molecular Formula	C11H7Cl2NO2
Molecular Weight	256.09 g/mol
Synonyms	7-Chloro-3-(chloroacetyl)-1H-indole-2-carboxaldehyde; 7-Chloro-2-formyl-1H-indole-3-acetyl chloride; 7-Chloro-1H-indole-2,3-dicarboxaldehyde, 3-(chloroacetyl) derivative; 7-Chlorooxindole-3-acetyl chloride; 7-Chloro-2-oxoindoline-3-acetyl chloride; 7-Chloro-3-(2-chloro-2-oxoethyl)-1H-indol-2(3H)-one; 863289-28-5
EINECS	Contact for details

Quality Control

Our 7-Chloro-α-Oxo-1H-Indole-3-Acetyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive synthetic applications. Production adheres to cGMP guidelines where applicable, and each lot is supported by a comprehensive Certificate of Analysis (COA). The COA includes data from multiple analytical techniques such as HPLC, NMR, and IR spectroscopy to confirm identity, purity, and the absence of critical impurities. We are committed to meeting the stringent specifications required by our partners in the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Keep away from strong bases and oxidizing agents. Ensure the storage area is well-ventilated.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.