Description

Maropitant Citrate Salt is a high-purity, non-peptidic neurokinin-1 (NK1) receptor antagonist. This compound is of significant commercial and research interest due to its potent antiemetic properties, specifically targeting substance P-mediated pathways. It is primarily utilized in the pharmaceutical and veterinary sectors for the development and formulation of anti-vomiting medications. The product is supplied under stringent quality control to ensure batch-to-batch consistency for critical applications.

Application

• Active Pharmaceutical Ingredient (API) in antiemetic drug formulations for human and veterinary use.
• Reference Standard for analytical method development and quality control in pharmaceutical laboratories.
• Biochemical Research for studying NK1 receptor mechanisms and neuropharmacology.
• Veterinary Medicine as a key component in treatments for acute vomiting in dogs and cats.
• Preclinical Development for efficacy and safety studies of new therapeutic agents.
• Process Chemistry as an intermediate for the synthesis of related chemical entities.

Basic Information

Product Name	Maropitant Citrate Salt
CAS No.	862543-54-2
Molecular Formula	C32H36F2N2O · C6H8O7
Molecular Weight	678.73 g/mol
Synonyms	Maropitant Citrate; (2S,3S)-2-Benzhydryl-N-[(5-tert-butyl-2-methoxyphenyl)methyl]quinuclidin-3-amine citrate salt; 1-[2-Benzhydryl-3-[(5-tert-butyl-2-methoxybenzyl)amino]quinuclidine] citrate; Cerenia (Veterinary Brand Name); NK1 Receptor Antagonist; Maropitant (base); (2S,3S)-N-[(5-tert-Butyl-2-methoxyphenyl)methyl]-2-(diphenylmethyl)-1-azabicyclo[2.2.2]octan-3-amine citrate
EINECS	Contact for details

Quality Control

Our Maropitant Citrate Salt is manufactured and tested to meet exacting standards suitable for pharmaceutical research and development. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC and other validated methods. We provide full traceability and Certificates of Analysis (COA) are available upon request to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%; Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.