Description

(2S,3S,11Br)-9,10-Dimethoxy-3-(2-Methylpropyl)-1H,2H,3H,4H,6H,7H,11Bh-Pyrido[2,1-A]Isoquinolin-2-Ol is a complex, chiral alkaloid derivative with a brominated pyridoisoquinoline core structure. This compound is of significant interest for its potential as a high-value pharmaceutical intermediate or research chemical in medicinal chemistry programs. It is primarily sought by R&D organizations and fine chemical manufacturers engaged in the synthesis of novel bioactive molecules, particularly within the fields of neuroscience and oncology.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a scaffold or precursor in structure-activity relationship (SAR) studies to explore new therapeutic targets.
• Biochemical Tool Compound: Potential application as a probe or inhibitor in biochemical and pharmacological assays to study specific biological pathways.
• Organic Synthesis Reference Standard: Employed as a high-purity standard for analytical method development and validation in synthetic chemistry.
• Asymmetric Synthesis: Utilized in the development of novel asymmetric catalytic reactions due to its defined stereochemistry.

Basic Information

Product Name	(2S,3S,11Br)-9,10-Dimethoxy-3-(2-Methylpropyl)-1H,2H,3H,4H,6H,7H,11Bh-Pyrido[2,1-A]Isoquinolin-2-Ol
CAS No.	862377-27-3
Molecular Formula	C22H30BrNO3
Molecular Weight	436.39 g/mol
Synonyms	9,10-Dimethoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-ol, (2S,3S,11bR)-rel-; (2S,3S,11bR)-9,10-Dimethoxy-3-(2-methylpropyl)-1,2,3,4,6,7,11b-octahydro-pyrido[2,1-a]isoquinolin-2-ol; Brominated Tetrahydroprotoberberine Derivative; Pyridoisoquinoline Alkaloid Derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality management systems. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and MS to confirm identity, chiral purity, and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure full traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.