Description

2-Amino-4-(4-tert-Butylphenyl)-5-Methylthiophene-3-Carboxamide is a high-purity, synthetically valuable heterocyclic building block. This compound is a critical intermediate in the research and development of advanced organic materials and active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Serves as a core structure for developing new active ingredients for crop protection and pest management solutions.
• Organic Electronic Materials: Used in the research of organic semiconductors, OLEDs, and other electronic materials due to its thiophene-based conjugated system.
• Dye & Pigment Synthesis: Acts as a precursor for specialized dyes and pigments requiring specific light-absorption properties.
• Chemical Research & Development: Employed as a versatile building block in academic and industrial laboratories for methodology development and novel compound library synthesis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the scale-up and production of client-specific target molecules.

Basic Information

Product Name	2-Amino-4-(4-tert-Butylphenyl)-5-Methylthiophene-3-Carboxamide
CAS No.	861451-49-2
Molecular Formula	C₁₆H₂₀N₂OS
Molecular Weight	288.41 g/mol
Synonyms	2-Amino-4-(4-tert-butylphenyl)-5-methylthiophene-3-carboxamide; 4-(4-tert-Butylphenyl)-2-amino-5-methylthiophene-3-carboxamide; 5-Methyl-2-amino-4-(4-tert-butylphenyl)thiophene-3-carboxamide; 861451-49-2; tert-Butylphenyl methylthiophene carboxamide derivative
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-4-(4-tert-Butylphenyl)-5-Methylthiophene-3-Carboxamide is produced under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee consistent quality and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.