Description

5-(4-tert-Butyl-Phenyl)-4-Methyl-Thiophene-2-Carboxylic Acid is a high-purity, functionalized thiophene derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines a sterically hindered tert-butylphenyl group with a reactive carboxylic acid moiety on a thiophene core. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for molecules targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Active Ingredient Synthesis: Used in the synthesis of advanced herbicides, fungicides, and insecticides, where the thiophene scaffold contributes to biological activity.
• Material Science & Organic Electronics: Serves as a precursor for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Ligand & Catalyst Development: The carboxylic acid group allows for functionalization into complex ligands for metal-organic frameworks (MOFs) or asymmetric catalysis.
• Chemical Research & Process Development: Employed in academic and industrial laboratories for method development, scale-up studies, and exploring new chemical reactions.
• Custom Synthesis & Contract Manufacturing: A starting material for the custom synthesis of complex, proprietary compounds for clients in life sciences.

Basic Information

Item	Details
Product Name	5-(4-tert-Butyl-Phenyl)-4-Methyl-Thiophene-2-Carboxylic Acid
CAS No.	861432-72-6
Molecular Formula	C16H18O2S
Molecular Weight	274.38 g/mol
Synonyms	4-Methyl-5-[4-(1,1-dimethylethyl)phenyl]-2-thiophenecarboxylic acid; 5-(4-tert-Butylphenyl)-4-methylthiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 5-[4-(1,1-dimethylethyl)phenyl]-4-methyl-; 4-Methyl-5-(4-tert-butylphenyl)thiophene-2-carboxylic acid; TBPTCA (abbreviation); 5-(p-tert-Butylphenyl)-4-methyl-2-thiophenecarboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 5-(4-tert-Butyl-Phenyl)-4-Methyl-Thiophene-2-Carboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) including purity (HPLC), identity confirmation (NMR, IR), and impurity profile is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.