Description

2-Amino-4-(4-Isobutylphenyl)-5-Methylthiophene-3-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its specific thiophene-based molecular architecture. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), where its unique structure enables precise molecular modifications. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates and novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Employed in the construction of more complex heterocyclic compounds due to its reactive amino and nitrile functional groups.
• Material Science Research: Investigated for potential applications in the development of organic electronic materials and specialty polymers.

Basic Information

Product Name	2-Amino-4-(4-Isobutylphenyl)-5-Methylthiophene-3-Carbonitrile
CAS No.	861408-82-4
Molecular Formula	C16H18N2S
Molecular Weight	270.40 g/mol
Synonyms	2-Amino-4-(4-isobutylphenyl)-5-methylthiophene-3-carbonitrile; 5-Methyl-2-amino-4-(4-isobutylphenyl)thiophene-3-carbonitrile; 4-(4-Isobutylphenyl)-2-amino-5-methylthiophene-3-carbonitrile; 2-Amino-5-methyl-4-(4-isobutylphenyl)thiophene-3-carbonitrile; Thiophene-3-carbonitrile, 2-amino-4-(4-isobutylphenyl)-5-methyl-; CAS 861408-82-4
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(4-Isobutylphenyl)-5-Methylthiophene-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.