Description

N'-[5-([1,1'-Biphenyl]-4-Ylcarbonyl)-1,3-Thiazol-2-Yl]-N,n-Dimethyliminoformamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in the fields of oncology and antiviral treatments. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel small-molecule drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic entities.
• Kinase Inhibitor Development: Serves as a core scaffold or precursor in the development of protein kinase inhibitors for cancer therapy.
• Chemical Biology Probes: Utilized in the creation of molecular probes to study enzyme function and cellular signaling mechanisms.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Employed in university and institutional labs for cutting-edge research in organic synthesis and drug design methodologies.

Basic Information

Product Name	N'-[5-([1,1'-Biphenyl]-4-Ylcarbonyl)-1,3-Thiazol-2-Yl]-N,n-Dimethyliminoformamide
CAS No.	861211-31-6
Molecular Formula	C25H21N3O2S
Molecular Weight	427.52 g/mol
Synonyms	N'-[5-(4-Biphenylylcarbonyl)-2-thiazolyl]-N,N-dimethylformamidine; N,N-Dimethyl-N'-[5-(4-phenylbenzoyl)-1,3-thiazol-2-yl]formamidine; 2-Thiazolamine, N-[5-([1,1'-biphenyl]-4-ylcarbonyl)-2-thiazolyl]-N,N-dimethyl-; Biphenyl-thiazole formamidine derivative; 861211-31-6; Advanced kinase inhibitor intermediate; Biphenyl carbonyl thiazole dimethylformamidine
EINECS	Contact for details

Quality Control

Our N'-[5-([1,1'-Biphenyl]-4-Ylcarbonyl)-1,3-Thiazol-2-Yl]-N,n-Dimethyliminoformamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and rigorous control of residual solvents and impurities to meet the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.