Description

4-Bromo-5,6,7,8-tetrahydro-1-methoxyisoquinoline is a high-purity, functionalized isoquinoline derivative, a crucial building block in advanced organic synthesis. Its value lies in its unique bromine and methoxy substituents on the tetrahydroisoquinoline scaffold, which enable precise chemical modifications for creating complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and fine chemicals. The CAS number for this product is 861136-83-6.

Application

This versatile chemical intermediate is primarily utilized in research and development, as well as in the synthesis of more complex molecules. Key application areas include:

• Pharmaceutical Research: Serves as a key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets, due to the privileged tetrahydroisoquinoline structure.
• Agrochemical Development: Used in the research and synthesis of new pesticides and herbicides, where the bromine atom offers a handle for further functionalization.
• Material Science: Acts as a building block for creating specialized ligands, catalysts, or organic electronic materials.
• Academic & Contract Research: Employed in universities and CROs (Contract Research Organizations) for method development and exploratory chemistry projects.
• Fine Chemical Synthesis: Integral in multi-step synthetic routes for producing high-value, complex organic compounds for various industrial applications.

Basic Information

Product Name	4-Bromo-5,6,7,8-Tetrahydro-1-Methoxyisoquinoline
CAS No.	861136-83-6
Molecular Formula	C₁₀H₁₂BrNO
Molecular Weight	242.11 g/mol
Synonyms	4-Bromo-1-methoxy-5,6,7,8-tetrahydroisoquinoline; 1-Methoxy-4-bromo-5,6,7,8-tetrahydroisoquinoline; 5,6,7,8-Tetrahydro-1-methoxy-4-bromoisoquinoline; 4-Bromo-1-methoxy-5,6,7,8-tetrahydro-isoquinoline; 861136-83-6
EINECS	Contact for details

Quality Control

Our 4-Bromo-5,6,7,8-tetrahydro-1-methoxyisoquinoline is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a Certificate of Analysis (COA) with every shipment, detailing all critical quality parameters. Our commitment to cGMP (current Good Manufacturing Practice) standards ensures reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.