Description

Ethanone, 2,2,2-Trifluoro-1-(1H-Pyrrolo[2,3-B]Pyridin-3-Yl)- is a high-value trifluoromethyl ketone derivative that serves as a critical synthetic intermediate. Its molecular architecture, featuring a fused pyrrolopyridine core, makes it an essential building block for constructing complex heterocyclic compounds. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for advanced synthesis programs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapeutics.
• Agrochemical Research: Used in developing advanced active ingredients for crop protection products.
• Material Science: Building block for specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: Versatile reagent for introducing the trifluoroacetyl group into complex molecular frameworks.
• Academic & Contract Research: Employed in medicinal chemistry and process development research within universities and CROs.

Basic Information

Product Name	Ethanone, 2,2,2-Trifluoro-1-(1H-Pyrrolo[2,3-B]Pyridin-3-Yl)-
CAS No.	860651-18-9
Molecular Formula	C9H5F3N2O
Molecular Weight	214.15 g/mol
Synonyms	2,2,2-Trifluoro-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)ethanone; 1-(1H-Pyrrolo[2,3-b]pyridin-3-yl)-2,2,2-trifluoroethanone; 3-Trifluoroacetyl-7-azaindole; 3-Trifluoroacetyl-1H-pyrrolo[2,3-b]pyridine; 7-Azaindole-3-trifluoromethyl ketone; TFAK-7AI; 860651-18-9
EINECS	Contact for details

Quality Control

Our production of Ethanone, 2,2,2-Trifluoro-1-(1H-Pyrrolo[2,3-B]Pyridin-3-Yl)- adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided with each shipment. We support development and cGMP manufacturing needs with traceable documentation and reliable batch-to-batch reproducibility.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.