Description

1,1-Dimethylethyl-4-[7-(Aminocarbonyl)-5-Bromo-1H-Indol-3-Yl]-1-Piperidine Carboxylate CAS NO 860625-18-9 is a high-purity, advanced pharmaceutical intermediate featuring a complex indole-piperidine core structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting specific biological pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop compounds with improved efficacy and pharmacokinetic profiles.
• Protease Inhibitor Development: Serves as a core scaffold for the development of inhibitors targeting specific enzymes, leveraging its bromo-indole and carboxamide functionalities.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying biological pathways and target validation in early-stage drug discovery.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, non-commercial compounds for preclinical and clinical trial applications.
• Academic Research: Utilized in university and institutional laboratories for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	1,1-Dimethylethyl-4-[7-(Aminocarbonyl)-5-Bromo-1H-Indol-3-Yl]-1-Piperidine Carboxylate
CAS No.	860625-18-9
Molecular Formula	C19H24BrN3O3
Molecular Weight	422.32 g/mol
Synonyms	tert-Butyl 4-(7-carbamoyl-5-bromo-1H-indol-3-yl)piperidine-1-carboxylate; 5-Bromo-3-(1-Boc-piperidin-4-yl)-1H-indole-7-carboxamide; 1-Boc-4-(5-Bromo-7-carbamoylindol-3-yl)piperidine; 860625-18-9; 1,1-Dimethylethyl 4-[7-(aminocarbonyl)-5-bromo-1H-indol-3-yl]-1-piperidinecarboxylate; BOC-5-Bromo-7-Carbamoylindole-3-Piperidine; 5-Bromo-7-carbamoyl-3-(1-N-Boc-piperidin-4-yl)indole
EINECS	Contact for details

Quality Control

Our 1,1-Dimethylethyl-4-[7-(Aminocarbonyl)-5-Bromo-1H-Indol-3-Yl]-1-Piperidine Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.