Description

5-Bromo-Indoline-7-Carboxylic Acid Methyl Ester is a high-purity, versatile brominated indoline derivative serving as a critical synthetic intermediate. Its value lies in providing a functionalized scaffold for constructing complex molecules in advanced research and development. This compound is essential for pharmaceutical chemists and R&D laboratories engaged in medicinal chemistry, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its modifiable bromine and ester functional groups.
• Agrochemical Development: Intermediate for creating novel crop protection agents and pesticides.
• Organic Synthesis: Versatile precursor for synthesizing more complex heterocyclic compounds and fine chemicals.
• Academic & Institutional R&D: Employed in university and research institute laboratories for developing new synthetic methodologies and exploring chemical space.
• Material Science Precursor: Potential starting material for the development of organic electronic materials and functional dyes.

Basic Information

Product Name	5-Bromo-Indoline-7-Carboxylic Acid Methyl Ester
CAS No.	860624-88-0
Molecular Formula	C10H10BrNO2
Molecular Weight	256.10 g/mol
Synonyms	Methyl 5-bromo-2,3-dihydro-1H-indole-7-carboxylate; 5-Bromo-2,3-dihydro-1H-indole-7-carboxylic acid methyl ester; 5-Bromoindoline-7-carboxylic Acid Methyl Ester; 860624-88-0; 5-Bromo-7-(methoxycarbonyl)indoline; Methyl 5-bromoindoline-7-carboxylate; 5-Bromo-1H-indole-7-carboxylic acid, 2,3-dihydro-, methyl ester
EINECS	Contact for details

Quality Control

Our 5-Bromo-Indoline-7-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical R&D and advanced synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.