Description

5-Cyano-3-Methylthiophene-2-Boronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. This compound matters for its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex heterocyclic architectures. Pharmaceutical, agrochemical, and advanced materials researchers need it for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used to create novel fungicides and herbicides with improved efficacy and environmental profiles.
• Material Science Research: Serves as a monomer or building block for developing conjugated polymers and organic electronic materials like OLEDs and OFETs.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and inhibitors for studying biological pathways.
• Ligand and Catalyst Development: Utilized to synthesize novel ligands for transition metal catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	5-Cyano-3-Methylthiophene-2-Boronic Acid
CAS No.	860617-72-7
Molecular Formula	C7H8BNO2S
Molecular Weight	181.02 g/mol
Synonyms	(5-Cyano-3-methyl-2-thienyl)boronic acid; 3-Methyl-5-cyanothiophene-2-boronic acid; 2-Borono-5-cyano-3-methylthiophene; 5-Cyano-3-methylthiophene-2-boronic acid pinacol ester (common derivative); 860617-72-7; 5-CN-3-Me-thiophene-2-B(OH)2
EINECS	Contact for details

Quality Control

Our 5-Cyano-3-Methylthiophene-2-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with stringent industry standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.