Description

4-Oxo-1-(3-Thienyl)-Cyclohexanecarbonitrile is a high-purity organic intermediate featuring a unique cyclohexanone core substituted with a thiophene ring and a nitrile group. This compound matters as a versatile and critical building block for the synthesis of complex molecules in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing complex heterocyclic architectures.
• Agrochemical Synthesis: Serves as a precursor for developing novel herbicides, fungicides, or insecticides with potentially new modes of action.
• Material Science Research: Used in the development of organic semiconductors, conductive polymers, or advanced organic frameworks due to its electron-rich thiophene moiety.
• Chemical Biology Probes: Employed as a scaffold for creating molecular probes to study enzyme function or cellular pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-Oxo-1-(3-Thienyl)-Cyclohexanecarbonitrile
CAS No.	860160-01-6
Molecular Formula	C11H11NOS
Molecular Weight	205.27 g/mol
Synonyms	1-(Thiophen-3-yl)-4-oxocyclohexanecarbonitrile; 4-Oxo-1-(thiophen-3-yl)cyclohexanecarbonitrile; 1-(3-Thienyl)-4-oxocyclohexanecarbonitrile; 4-Oxo-1-(3-thienyl)cyclohexanecarbonitrile; Cyclohexanecarbonitrile, 4-oxo-1-(3-thienyl)-; 860160-01-6 (CAS Name)
EINECS	Contact for details

Quality Control

Our 4-Oxo-1-(3-Thienyl)-Cyclohexanecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.