Description

4-Methoxy-2-Nitrophenylboronic Acid is a versatile boronic acid derivative characterized by its methoxy and nitro substituents, making it a valuable building block in modern synthetic chemistry. Its primary value lies in its role as a key intermediate in Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients, as well as in material science for creating advanced organic electronic materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those containing complex biaryl scaffolds for oncology, CNS, and anti-infective therapies.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides with targeted activity and improved environmental profiles.
• Material Science Research: Serves as a building block for organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and other functional organic materials.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and in the development of new catalytic systems.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological processes and enzyme functions.
• Academic & R&D Laboratories: A fundamental reagent for methodological development in organic synthesis and cross-coupling reaction optimization.

Basic Information

Product Name	4-Methoxy-2-Nitrophenylboronic Acid
CAS No.	860034-09-9
Molecular Formula	C7H8BNO5
Molecular Weight	197.96 g/mol
Synonyms	(4-Methoxy-2-nitrophenyl)boronic Acid; 2-Nitro-4-methoxybenzeneboronic Acid; 4-Methoxy-2-nitrobenzeneboronic Acid; B-(4-Methoxy-2-nitrophenyl)boronic Acid; 860034-09-9; 4-Methoxy-2-nitrophenyl-Boronic Acid
EINECS	Contact for details

Quality Control

Our 4-Methoxy-2-Nitrophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF Titration)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.