Description

1H-Indole-1-Carboxylic Acid, 5-(2-Chloroethyl)-2,3-Dihydro-, 1,1-Dimethylethyl Ester is a high-purity, synthetically valuable indole derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. It is primarily required by R&D and production teams in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Building block for developing new-generation herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Organic Synthesis: Versatile reagent for constructing indole-based molecular scaffolds in medicinal and combinatorial chemistry.
• Material Science: Potential monomer or additive in the research of specialty polymers and advanced organic electronic materials.
• Contract Research & Development (CRO/CMO): Supplied to research organizations for custom synthesis and process development projects.

Basic Information

Product Name	1H-Indole-1-Carboxylic Acid, 5-(2-Chloroethyl)-2,3-Dihydro-, 1,1-Dimethylethyl Ester
CAS No.	860024-94-8
Molecular Formula	C16H20ClNO2
Molecular Weight	293.79 g/mol
Synonyms	tert-Butyl 5-(2-chloroethyl)-2,3-dihydro-1H-indole-1-carboxylate; 5-(2-Chloroethyl)-2,3-dihydro-1H-indole-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-5-(2-chloroethyl)indoline; Boc-5-(2-chloroethyl)indoline; 860024-94-8
EINECS	Contact for details

Quality Control

Our production of this intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques (HPLC, GC, NMR) to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all relevant specifications. We support development under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.