Description

1-(4-Fluoro-2,3-Dihydro-1H-Indol-1-Yl)-Ethanone is a high-purity fluorinated indole derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for creating new compounds with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Material Science Research: Serves as a precursor for specialty chemicals and functional materials, including organic semiconductors and liquid crystals.
• Academic & Contract Research: Employed in academic laboratories and CROs (Contract Research Organizations) for method development and exploratory chemistry projects.
• Fluorine Chemistry: Acts as a versatile substrate for further fluorination or functionalization reactions to create a library of related compounds.

Basic Information

Product Name	1-(4-Fluoro-2,3-Dihydro-1H-Indol-1-Yl)-Ethanone
CAS No.	860024-83-5
Molecular Formula	C10H10FNO
Molecular Weight	179.19 g/mol
Synonyms	1-Acetyl-4-fluoro-2,3-dihydro-1H-indole; 4-Fluoro-1-indolin-1-ylethanone; 4-Fluoro-1-(1-acetyl)indoline; 1-(4-Fluoro-2,3-dihydroindol-1-yl)ethanone; 4-Fluoroindoline-1-acetone; N-Acetyl-4-fluoroindoline; 860024-83-5; 4-Fluoro-N-acetylindoline
EINECS	Contact for details

Quality Control

Our 1-(4-Fluoro-2,3-Dihydro-1H-Indol-1-Yl)-Ethanone is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.