Description

3-Bromo-1,5-Naphthyridin-2(1H)-One is a high-value brominated naphthyridinone derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique halogenated heterocyclic structure makes it an essential building block for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Serves as a monomer or functional unit in the creation of organic electronic materials, such as OLEDs or conductive polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.
• Academic & Contract Research: Fundamental reagent for methodological studies in cross-coupling reactions and heterocyclic chemistry.
• Custom Synthesis: Starting material for the contract manufacturing of specialized, high-value fine chemicals.

Basic Information

Product Name	3-Bromo-1,5-Naphthyridin-2(1H)-One
CAS No.	859986-64-4
Molecular Formula	C8H5BrN2O
Molecular Weight	225.04 g/mol
Synonyms	3-Bromo-1,5-naphthyridin-2(1H)-one; 3-Bromo-1H-1,5-naphthyridin-2-one; 2(1H)-Naphthyridinone, 3-bromo-1,5-; 3-Bromonaphthyridinone; 1,5-Naphthyridin-2(1H)-one, 3-bromo-; 3-Bromo-1,5-dihydro-2H-1,5-naphthyridin-2-one
EINECS	Contact for details

Quality Control

Our 3-Bromo-1,5-Naphthyridin-2(1H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP and ISO 9001 compliant production for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.