Description

1-[5-(2-Thienyl)-1H-Pyrazol-3-Yl]Methanamine is a high-purity heterocyclic building block featuring a fused pyrazole-thiophene core with a primary amine functional group. This compound is of significant value in medicinal chemistry and materials science research for constructing novel molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Serves as a core structure for designing new herbicides, fungicides, and insecticides with potential novel modes of action.
• Ligand Synthesis: Used in coordination chemistry to create chelating ligands for catalysis or metal-organic frameworks (MOFs).
• Material Science Precursor: Employed in the synthesis of organic semiconductors, conductive polymers, and other advanced electronic materials due to its thiophene moiety.
• Chemical Biology Probe: Acts as a versatile handle for bioconjugation and the development of activity-based probes for target identification.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up services.

Basic Information

Product Name	1-[5-(2-Thienyl)-1H-Pyrazol-3-Yl]Methanamine
CAS No.	859850-80-9
Molecular Formula	C8H9N3S
Molecular Weight	179.24 g/mol
Synonyms	1-(5-(Thiophen-2-yl)-1H-pyrazol-3-yl)methanamine; (5-(Thiophen-2-yl)-1H-pyrazol-3-yl)methanamine; 1-(5-(2-Thienyl)-1H-pyrazol-3-yl)methylamine; 3-(Aminomethyl)-5-(2-thienyl)-1H-pyrazole; 5-(2-Thienyl)-1H-pyrazole-3-methanamine; 1H-Pyrazole-3-methanamine, 5-(2-thienyl)-; 859850-80-9
EINECS	Contact for details

Quality Control

Our 1-[5-(2-Thienyl)-1H-Pyrazol-3-Yl]Methanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment. We support cGMP (current Good Manufacturing Practice) standards for advanced applications and can accommodate custom purity requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.