Description

Methyl 2-(tert-Butoxycarbonylamino)Thiophene-3-Carboxylate is a high-purity, protected amino acid derivative featuring a thiophene heterocycle, serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of drug candidates, particularly those containing thiophene-based heterocycles with potential biological activity.
• Peptidomimetic Research: Used in the design and synthesis of peptidomimetics and constrained peptides, where the tert-butoxycarbonyl (Boc) group provides orthogonal protection for the amine functionality.
• Agrochemical Development: Serves as a precursor in the creation of novel herbicides, fungicides, or insecticides that incorporate the thiophene moiety.
• Material Science: Employed in the synthesis of organic semiconductors, conductive polymers, or liquid crystals where thiophene derivatives are essential components.
• Chemical Biology Probes: Utilized in the construction of labeled compounds or probes for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring specific, protected heterocyclic carboxylic acid derivatives.

Basic Information

Product Name	Methyl 2-(tert-Butoxycarbonylamino)Thiophene-3-Carboxylate
CAS No.	859204-24-3
Molecular Formula	C11H15NO4S
Molecular Weight	257.30 g/mol
Synonyms	2-[(tert-Butoxycarbonyl)amino]-3-thiophenecarboxylic acid methyl ester; Methyl 2-[(tert-butoxycarbonyl)amino]thiophene-3-carboxylate; 3-Thiophenecarboxylic acid, 2-[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester; Boc-3-Thienylglycine methyl ester; 2-(Boc-amino)thiophene-3-carboxylic acid methyl ester; Methyl 2-(Boc-amino)-3-thiophenecarboxylate; 2-(tert-Butoxycarbonylamino)thiophene-3-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 2-(tert-Butoxycarbonylamino)Thiophene-3-Carboxylate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and scale-up applications. All materials are characterized by modern analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound is sensitive to strong acids and organic solvents; keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.