Description

2,5-Dimethyl 3-Nitrothiophene-2,5-Dicarboxylate is a high-value, multi-functional nitro-thiophene derivative used as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile precursor in the development of complex heterocyclic molecules, particularly in the pharmaceutical and agrochemical sectors. Industrial and R&D chemists need it for applications ranging from the synthesis of active pharmaceutical ingredients (APIs) to the creation of novel materials and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of complex thiophene-based drug candidates, including potential kinase inhibitors and anti-inflammatory agents.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, and insecticides that leverage the thiophene scaffold for bioactivity.
• Material Science Research: Used in the synthesis of organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to its electron-deficient nitro-thiophene core.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing specialized dyes and pigments where the nitro and ester functionalities allow for color tuning and stability.
• Academic & Industrial R&D: Employed in method development and exploratory chemistry for creating new heterocyclic libraries and testing novel synthetic pathways.

Basic Information

Product Name	2,5-Dimethyl 3-Nitrothiophene-2,5-Dicarboxylate
CAS No.	858840-42-3
Molecular Formula	C9H7NO6S
Molecular Weight	257.22 g/mol
Synonyms	Dimethyl 3-nitrothiophene-2,5-dicarboxylate; 3-Nitro-2,5-thiophenedicarboxylic Acid Dimethyl Ester; 2,5-Thiophenedicarboxylic acid, 3-nitro-, dimethyl ester; Methyl 3-nitrothiophene-2,5-dicarboxylate; 3-Nitrothiophene-2,5-dicarboxylic acid dimethyl ester; 2,5-Dimethyl 3-nitrothiophene-2,5-dicarboxylate
EINECS	Contact for details

Quality Control

Our 2,5-Dimethyl 3-Nitrothiophene-2,5-Dicarboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, and we support customer audits and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon) to preserve stability and prevent degradation.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.