Description

3-Formyl-6-Methoxy-1H-Indole-2-Carboxylic Acid is a high-purity, multi-functional indole derivative serving as a critical advanced intermediate in organic synthesis. Its unique molecular structure, featuring both formyl and carboxylic acid functional groups, makes it an exceptionally versatile building block for constructing complex heterocyclic systems. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex indole-based drug candidates, particularly for oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the indole scaffold for biological activity.
• Organic Synthesis Building Block: The reactive aldehyde and acid groups enable its use in condensation, cyclization, and coupling reactions to create novel heterocyclic libraries for screening.
• Material Science Research: Investigated as a monomer or functional component in the development of specialty polymers and organic electronic materials.
• Biochemical Probe Development: Serves as a starting material for synthesizing fluorescent tags or molecular probes used in biochemical assays and diagnostic research.

Basic Information

Product Name	3-Formyl-6-Methoxy-1H-Indole-2-Carboxylic Acid
CAS No.	858752-19-9
Molecular Formula	C11H9NO4
Molecular Weight	219.19 g/mol
Synonyms	6-Methoxy-3-formyl-1H-indole-2-carboxylic acid; 1H-Indole-2-carboxylic acid, 3-formyl-6-methoxy-; 3-Formyl-6-methoxyindole-2-carboxylic acid; 6-Methoxy-1H-indole-2-carboxylic acid-3-carboxaldehyde; 858752-19-9
EINECS	Contact for details

Quality Control

Our production of 3-Formyl-6-Methoxy-1H-Indole-2-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical research and development processes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with global regulatory frameworks, and specifications can be aligned with cGMP or other relevant standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.