Description

3-Formyl-5,6-Dimethoxy-1H-Indole-2-Carboxylic Acid Methyl Ester is a high-purity, multi-functional indole derivative that serves as a critical advanced intermediate in organic synthesis. Its unique molecular structure, featuring both formyl and ester functional groups on the indole core, makes it an exceptionally versatile building block for constructing complex heterocyclic compounds. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) agents, anti-cancer compounds, and other biologically active indole-based molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the indole scaffold for enhanced activity.
• Organic Synthesis Building Block: The reactive aldehyde and ester groups enable its use in various condensation, cyclization, and functional group transformation reactions to create complex heterocyclic libraries.
• Material Science Research: Serves as a monomer or precursor for functional organic materials, such as organic semiconductors, dyes, and photoresists, due to its conjugated indole system.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in synthetic organic chemistry and for exploring new reaction pathways.

Basic Information

Item	Details
Product Name	3-Formyl-5,6-Dimethoxy-1H-Indole-2-Carboxylic Acid Methyl Ester
CAS No.	858749-33-4
Molecular Formula	C₁₃H₁₃NO₅
Molecular Weight	263.25 g/mol
Synonyms	Methyl 3-Formyl-5,6-Dimethoxy-1H-indole-2-carboxylate; 5,6-Dimethoxy-3-formyl-1H-indole-2-carboxylic Acid Methyl Ester; 1H-Indole-2-carboxylic acid, 3-formyl-5,6-dimethoxy-, methyl ester; 858749-33-4; Methyl 5,6-dimethoxy-3-formylindole-2-carboxylate
EINECS	Contact for details

Quality Control

Every batch of 3-Formyl-5,6-Dimethoxy-1H-Indole-2-Carboxylic Acid Methyl Ester is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be stored away from light. For long-term storage, consider keeping the container under an inert atmosphere to minimize potential oxidation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.