Description

6-Cyclopropylbenzo[D]Isothiazole-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Research: Serves as a building block for developing new generation pesticides and herbicides with specific activity profiles.
• Chemical Synthesis: Used in organic chemistry research for constructing complex benzoisothiazole-based scaffolds for material science and catalysis studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic & Industrial R&D: Utilized in discovery chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	6-Cyclopropylbenzo[D]Isothiazole-3-Carboxylic Acid
CAS No.	858671-75-7
Molecular Formula	C11H9NO2S
Molecular Weight	219.26 g/mol
Synonyms	6-Cyclopropyl-1,2-benzisothiazole-3-carboxylic acid; 6-Cyclopropylbenzo[d]isothiazole-3-carboxylic acid; 3-Carboxy-6-cyclopropylbenzo[d]isothiazole; 6-Cyclopropyl-1,2-benzisothiazol-3-carboxylic acid; 6-Cyclopropylbenzoisothiazole-3-carboxylic acid; 858671-75-7; 6-Cyclopropylbenzisothiazole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Cyclopropylbenzo[D]Isothiazole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and development standards. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 98.0% / ≥ 99.0% (High Purity Grades)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.