Description

4-Methyl-6-(1H-Pyrazol-1-Yl)Pyridin-3-Ylboronic Acid is a specialized boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation, which is essential for constructing complex molecular architectures. This high-purity intermediate is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for applications in drug discovery and advanced material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Suzuki-Miyaura Cross-Coupling Reactions: Functions as a versatile boronic acid coupling partner for constructing biaryl and heterobiaryl systems, a cornerstone of medicinal chemistry.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides requiring specific heterocyclic scaffolds.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors, electron-transport materials, and light-emitting compounds for electronic devices.
• Ligand Synthesis for Catalysis: Serves as a building block for creating novel bidentate or tridentate ligands used in homogeneous catalysis.
• Chemical Biology & Probe Development: Utilized in the creation of molecular probes and tags for studying biological processes and target engagement.

Basic Information

Product Name	4-Methyl-6-(1H-Pyrazol-1-Yl)Pyridin-3-Ylboronic Acid
CAS No.	858523-50-9
Molecular Formula	C9H10BN3O2
Molecular Weight	203.01 g/mol
Synonyms	4-Methyl-6-(1H-pyrazol-1-yl)pyridine-3-boronic acid; (4-Methyl-6-(1H-pyrazol-1-yl)pyridin-3-yl)boronic acid; 3-Pyridineboronic acid, 4-methyl-6-(1H-pyrazol-1-yl)-; 858523-50-9; 6-(1H-Pyrazol-1-yl)-4-methylpyridin-3-ylboronic acid; Boronic acid, B-[4-methyl-6-(1H-pyrazol-1-yl)-3-pyridinyl]-; 4-Methyl-6-(1-pyrazolyl)-3-pyridineboronic acid
EINECS	Contact for details

Quality Control

Our 4-Methyl-6-(1H-Pyrazol-1-Yl)Pyridin-3-Ylboronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All material is characterized by advanced analytical techniques including NMR and HPLC. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.