Description

4-Chloro-3-Methyl-1H-Indole is a halogenated indole derivative that serves as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both chloro and methyl substituents on the indole core, makes it a critical building block for constructing complex heterocyclic compounds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncological pathways.
• Agrochemical Synthesis: Building block for developing new generation herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science Research: Used in the development of organic semiconductors, photochromic materials, and advanced polymers due to its electron-rich indole structure.
• Biochemical Probe Development: Serves as a core structure for creating fluorescent tags, enzyme inhibitors, and receptor ligands for diagnostic and research applications.
• Organic Synthesis: A versatile reagent for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and electrophilic substitution reactions to create diverse chemical libraries.

Basic Information

Product Name	4-Chloro-3-Methyl-1H-Indole
CAS No.	858236-14-3
Molecular Formula	C9H8ClN
Molecular Weight	165.62 g/mol
Synonyms	4-Chloro-3-methylindole; 3-Methyl-4-chloroindole; 4-Chloro-3-methyl-1H-indole; 1H-Indole, 4-chloro-3-methyl-; 4-Chloro-3-methyl-1H-indole; 858236-14-3
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Methyl-1H-Indole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting compliance with cGMP and ICH Q7 guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.