Description

1-Acetyl-7-Bromoindolin-5-Amine is a high-purity, functionalized indoline derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of novel pharmaceutical intermediates and active ingredients. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive indoline core.
• Organic Synthesis Building Block: The acetyl and bromo functional groups make it a versatile substrate for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and further derivatization.
• Material Science Precursor: Employed in the research and development of organic semiconductors, dyes, and photoresponsive materials.
• Chemical Biology Probe: Useful for labeling studies and as a scaffold in fragment-based drug discovery (FBDD) campaigns.

Basic Information

Product Name	1-Acetyl-7-Bromoindolin-5-Amine
CAS No.	858193-23-4
Molecular Formula	C10H11BrN2O
Molecular Weight	255.11 g/mol
Synonyms	7-Bromo-1-acetylindolin-5-amine; 5-Amino-7-bromo-1-acetylindoline; 1-Acetyl-7-bromo-5-aminoindoline; 7-Bromo-5-amino-1-acetylindoline; 858193-23-4; 1H-Indol-5-amine, 7-bromo-2,3-dihydro-1-acetyl-
EINECS	Contact for details

Quality Control

Our 1-Acetyl-7-Bromoindolin-5-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.