Description

(2-Phenyl-1,3-thiazol-4-yl)methanamine hydrochloride is a high-purity organic salt with a defined heterocyclic structure, serving as a critical building block in advanced chemical synthesis. Its value lies in providing a functionalized thiazole core with a primary amine handle, essential for constructing complex molecules in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, or insecticides that incorporate the 2-phenylthiazole pharmacophore.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in catalytic systems or metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of organic semiconductors, dyes, or photoactive materials due to its conjugated thiazole system.
• Bioconjugation and Probe Development: The amine functionality allows for coupling to biomolecules or fluorescent tags, useful in creating diagnostic probes.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-specific projects requiring this precise chemical scaffold.

Basic Information

Product Name	(2-Phenyl-1,3-thiazol-4-yl)methanamine Hydrochloride
CAS No.	857997-89-8
Molecular Formula	C10H11ClN2S
Molecular Weight	226.72 g/mol
Synonyms	4-(Aminomethyl)-2-phenylthiazole Hydrochloride; 2-Phenyl-4-thiazolemethanamine Hydrochloride; 4-(Aminomethyl)-2-phenyl-1,3-thiazole Hydrochloride; (2-Phenyl-1,3-thiazol-4-yl)methylamine Hydrochloride; 1-(2-Phenylthiazol-4-yl)methanamine Hydrochloride; (2-Phenylthiazol-4-yl)methanamine HCl; 4-Thiazolemethanamine, 2-phenyl-, hydrochloride
EINECS	Contact for details

Quality Control

Our (2-Phenyl-1,3-thiazol-4-yl)methanamine hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.