Description

trans-2-(3-Fluoro-4-Methylphenyl)Cyclohexanol is a high-purity fluorinated cyclohexanol derivative, a key chiral intermediate in advanced organic synthesis. Its value lies in the precise stereochemistry and the fluorine atom, which are critical for modulating the biological activity and metabolic stability of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorine substituent enhances efficacy and environmental persistence.
• Chiral Catalyst/Ligand Precursor: Serves as a starting material for the preparation of sophisticated chiral auxiliaries, ligands, or catalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique optical or surface properties.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	trans-2-(3-Fluoro-4-Methylphenyl)Cyclohexanol
CAS No.	857872-81-2
Molecular Formula	C13H17FO
Molecular Weight	208.27 g/mol
Synonyms	trans-2-(3-Fluoro-4-methylphenyl)cyclohexan-1-ol; (1R,2R)-2-(3-Fluoro-4-methylphenyl)cyclohexanol; (1S,2S)-2-(3-Fluoro-4-methylphenyl)cyclohexanol; 2-(3-Fluoro-4-methylphenyl)cyclohexanol (trans-); 3-Fluoro-4-methyl-trans-2-phenylcyclohexanol; NSC 781106; FCHEM1-005332; AKOS005258065
EINECS	Contact for details

Quality Control

Our trans-2-(3-Fluoro-4-Methylphenyl)Cyclohexanol is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.