Description

Octahydro-1H-Isoindol-5-Ol is a saturated bicyclic organic compound featuring a fused cyclohexane-pyrrolidine structure with a hydroxyl substituent. This specific molecular architecture makes it a valuable and versatile chiral building block and intermediate in advanced organic synthesis. It is particularly sought after by research and development teams in the pharmaceutical and fine chemical industries for constructing complex, three-dimensional molecular frameworks.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Synthesis: Utilized as a precursor or auxiliary in catalytic asymmetric reactions to introduce stereochemical complexity.
• Ligand and Catalyst Development: Serves as a core structure for designing novel chiral ligands and organocatalysts.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, agrochemicals, and flavors & fragrances.
• Academic and Industrial R&D: Used in methodological research and process chemistry development within organic chemistry laboratories.

Basic Information

Product Name	Octahydro-1H-Isoindol-5-Ol
CAS No.	857363-11-2
Molecular Formula	C8H15NO
Molecular Weight	141.21 g/mol
Synonyms	5-Hydroxyoctahydro-1H-isoindole; (3aR,7aS)-Octahydro-1H-isoindol-5-ol; (3aR,7aS)-5-Hydroxyhexahydro-1H-isoindole; 1H-Isoindol-5-ol, octahydro-; Isoindolin-5-ol, hexahydro- (non-specific); Chiral Isoindoline Alcohol; Bicyclic Amino Alcohol Intermediate
EINECS	Contact for details

Quality Control

Our Octahydro-1H-Isoindol-5-Ol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination (HPLC, GC), identity confirmation (IR, NMR), and assay analysis to ensure it meets exacting standards for research and production use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (typical)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.