Description

2-Amino-4-(4-Pyridinyl)-5-Thiazolecarboxylic Acid Ethyl Ester is a high-purity, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents and agrochemicals, where its unique thiazole-pyridine core structure enables the creation of molecules with targeted biological activity. It is primarily needed by research institutions and industrial manufacturers in the life sciences sector, particularly those focused on medicinal chemistry, drug discovery, and the synthesis of specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, especially those targeting kinase inhibition or possessing antimicrobial properties.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Medicinal Chemistry: Serves as a versatile building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Organic Synthesis: Employed in academic and industrial R&D for the construction of complex nitrogen- and sulfur-containing heterocycles.
• Biochemical Tool Compound: Potential use in developing probes and inhibitors for studying biological pathways and enzyme functions.

Basic Information

Product Name	2-Amino-4-(4-Pyridinyl)-5-Thiazolecarboxylic Acid Ethyl Ester
CAS No.	857345-89-2
Molecular Formula	C11H11N3O2S
Molecular Weight	249.29 g/mol
Synonyms	Ethyl 2-Amino-4-(pyridin-4-yl)-1,3-thiazole-5-carboxylate; 4-(4-Pyridinyl)-2-amino-5-thiazolecarboxylic Acid Ethyl Ester; 2-Amino-4-(4-pyridyl)-5-thiazolecarboxylic acid ethyl ester; 5-Thiazolecarboxylic acid, 2-amino-4-(4-pyridinyl)-, ethyl ester; 4-Pyridin-4-yl-2-amino-thiazole-5-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(4-Pyridinyl)-5-Thiazolecarboxylic Acid Ethyl Ester is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.