Description

tert-Butyl 4-Iodo-3,5-Dimethyl-1H-Pyrazole-1-Carboxylate is a high-purity, versatile pyrazole derivative designed for advanced chemical synthesis. This compound serves as a critical building block in pharmaceutical and agrochemical research, enabling the introduction of a protected pyrazole moiety and an iodine handle for further functionalization. It is essential for medicinal chemists and process development scientists working on novel active ingredients, particularly in the development of kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting specific enzymes and receptors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Chemical Synthesis Building Block: The iodine atom and the tert-butyloxycarbonyl (Boc) protecting group allow for sequential cross-coupling and deprotection reactions to create diverse molecular libraries.
• Material Science Research: Potential monomer or ligand for constructing functional polymers or metal-organic frameworks (MOFs) with specific properties.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting exploratory chemistry and method development.

Basic Information

Product Name	tert-Butyl 4-Iodo-3,5-Dimethyl-1H-Pyrazole-1-Carboxylate
CAS No.	857283-71-7
Molecular Formula	C10H15IN2O2
Molecular Weight	322.15 g/mol
Synonyms	1-Boc-4-iodo-3,5-dimethylpyrazole; 4-Iodo-3,5-dimethyl-1H-pyrazole-1-carboxylic acid tert-butyl ester; tert-Butyl 4-iodo-3,5-dimethyl-1H-pyrazole-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-iodo-3,5-dimethylpyrazole; 3,5-Dimethyl-4-iodopyrazole-1-carboxylic acid tert-butyl ester; 4-Iodo-3,5-dimethylpyrazole-1-carboxylic acid tert-butyl ester; Boc-4-I-3,5-Me2-Pyrazole
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl 4-Iodo-3,5-Dimethyl-1H-Pyrazole-1-Carboxylate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.