Description

p-Dioxane-2-Thiol, 5,5,6-Trichloro- (6Ci) is a specialized organosulfur compound featuring a thiol group on a trichlorinated dioxane scaffold, serving as a versatile building block for advanced chemical synthesis. Its unique structure makes it a critical intermediate for developing novel materials and active pharmaceutical ingredients (APIs) where precise halogen and sulfur functionality is required. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific reactive handles into complex molecules.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its reactive thiol and halogen groups.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Employed to introduce functional groups into polymer chains, altering physical properties for high-performance materials.
• Chemical Research & Development: A valuable tool for academic and industrial R&D in exploring new organic reactions and heterocyclic chemistry.
• Cross-coupling Reactions: Acts as a substrate in various palladium-catalyzed cross-coupling reactions to form carbon-sulfur and carbon-carbon bonds.

Basic Information

Product Name	p-Dioxane-2-Thiol, 5,5,6-Trichloro- (6Ci)
CAS No.	857196-89-5
Molecular Formula	C4H3Cl3O2S
Molecular Weight	237.49 g/mol
Synonyms	5,5,6-Trichloro-1,4-dioxane-2-thiol; 5,5,6-Trichloro-2-mercapto-1,4-dioxane; 1,4-Dioxane-2-thiol, 5,5,6-trichloro-; 2-Mercapto-5,5,6-trichloro-1,4-dioxane; 5,5,6-Trichloro-2-sulfanyl-1,4-dioxane; p-Dioxane-2-thiol,5,5,6-trichloro-; (6Ci)-5,5,6-Trichloro-1,4-dioxane-2-thiol
EINECS	Contact for details

Quality Control

Our p-Dioxane-2-Thiol, 5,5,6-Trichloro- (6Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and industrial use. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP for advanced intermediates, supporting our global clientele in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Unknown Impurity	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.