Description

Carbamic Acid, [4-(2,5-Dihydro-2,5-Dioxo-1H-Pyrrol-1-Yl)Butyl]-, 1,1-Dimethylethyl Ester is a specialized chemical building block featuring a maleimide-protected amine group. This compound is critical for advanced organic synthesis, particularly in the development of pharmaceuticals and high-performance polymers, where controlled reactivity and functional group protection are paramount. It serves as a key intermediate for researchers and manufacturers in life sciences, specialty chemicals, and materials science sectors requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly where a protected amine linker is required for conjugation.
• Bioconjugation Reagent: Acts as a versatile linker for attaching drugs, probes, or labels to proteins, antibodies, or other biomolecules via thiol-maleimide chemistry.
• Polymer & Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers, hydrogels, and functionalized surfaces.
• Peptide Synthesis: Employed as a building block in solid-phase peptide synthesis (SPPS) to introduce specific functional handles.
• Research & Development: A valuable tool in academic and industrial R&D for exploring new chemical entities and novel synthetic pathways.
• Diagnostic Reagent Manufacturing: Used in the production of components for diagnostic assays and imaging agents.

Basic Information

Product Name	Carbamic Acid, [4-(2,5-Dihydro-2,5-Dioxo-1H-Pyrrol-1-Yl)Butyl]-, 1,1-Dimethylethyl Ester
CAS No.	857074-62-5
Molecular Formula	C13H20N2O4
Molecular Weight	268.31 g/mol
Synonyms	tert-Butyl N-[4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)butyl]carbamate; 1-(4-((tert-Butoxycarbonyl)amino)butyl)-1H-pyrrole-2,5-dione; Boc-Amino-PEG3-Maleimide; Boc-N-amido-PEG3-maleimide; Maleimide-PEG3-Boc-amine; N-Boc-1,8-diamino-3,6-dioxaoctane maleimide; N-(tert-Butoxycarbonyl)-4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)butan-1-amine
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, [4-(2,5-Dihydro-2,5-Dioxo-1H-Pyrrol-1-Yl)Butyl]-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.