Description

Sym-Homospermidine-D4 Trihydrochloride is a stable isotope-labeled analog of the naturally occurring polyamine homospermidine, specifically deuterated at four positions. This high-purity compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring accurate and reliable analytical results. It is primarily required by researchers and quality control laboratories in the pharmaceutical, biotechnology, and life science sectors for drug metabolism studies, pharmacokinetic research, and biomarker analysis.

Application

• Internal Standard for LC-MS/MS: Critical for the precise quantification of homospermidine in complex biological matrices like plasma, urine, and tissue homogenates.
• Pharmacokinetic and Drug Metabolism Studies (DMPK): Used to track the absorption, distribution, metabolism, and excretion (ADME) of polyamine-related drug candidates.
• Biomarker Research: Enables accurate measurement of polyamine levels in disease state studies, such as cancer and neurological disorders.
• Stable Isotope Dilution Assays: Provides a reference for developing highly specific and sensitive diagnostic assays.
• Method Development and Validation: Serves as a key component in establishing GLP/GMP-compliant analytical methods for regulatory submissions.
• Biochemical Pathway Analysis: Facilitates research into polyamine biosynthesis and catabolism in cellular systems.

Basic Information

Item	Detail
Product Name	Sym-Homospermidine-D4 Trihydrochloride
CAS No.	856869-03-9
Molecular Formula	C7H15D4N3 • 3HCl
Molecular Weight	Contact for details
Synonyms	Homospermidine-d4 Trihydrochloride; N-(3-Aminopropyl)-1,4-diaminobutane-d4 Trihydrochloride; 1,9-Diamino-5-azanonane-d4 Trihydrochloride; Spermidine Homolog-d4 Trihydrochloride; Isotope Labeled Homospermidine Trihydrochloride; Deuterated Polyamine Internal Standard; [2,2,3,3-2H4]-Homospermidine Trihydrochloride
EINECS	Contact for details

Quality Control

Every batch of Sym-Homospermidine-D4 Trihydrochloride is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We guarantee high chemical and isotopic purity suitable for sensitive mass spectrometry applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters including assay, isotopic enrichment, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.